
At fictional Princeton Plainsboro Teaching Hospital in New Jersey, prickly genius Dr. Gregory House tackles health mysteries as would a medical Sherlock Holmes, all the while playing mind games with colleagues that include his best friend, oncologist James Wilson. House, an acerbic infectious disease specialist, solves medical puzzles with the help of a team of young diagnosticians. Flawless instincts and unconventional thinking help earn House great respect, despite his brutal honesty and antisocial tendencies.

153 of 162 Mets games this season on Fubo

135 of 162 Yankees games this season on Fubo
A bus accident robs House of several hours, as his memory slowly returns, he realizes that one of his fellow passengers was exhibiting signs of a deadly illness, so he races to unlock the secrets in his brain.
House's murky memories of the bus crash test his friendship with Wilson and threaten to change their lives forever.
Still mourning the death of his girlfriend, Wilson resigns from Princeton Plainsboro; House must determine if he is responsible for the death of his best friend's girlfriend; Thirteen struggles to treat a patient objectively.
House and the team investigate a string of deaths centering around a single organ donor; they rush to save the only two surviving recipients; House auditions new best friends and uses a detective to spy on Wilson.